抗衰新視角:從“精氣血”理論到中式細胞延衰新方案

無限極
2025.09.12
探索中西融合整體抗衰新思路。

來源:無限極

封麵圖來源:攝圖網


皮膚老化、睡眠差、氣血不足、精力下降、jiyilijiantuidengshishuailaodechangjianbiaozheng。renleiduikangshuailaodetansuocongweitingzhi,zaiciguochengzhong,zhongyijiyujiqianniandeshijianjingyanjileiledutezhihui,erxiandaiyixuezepingjiekejishouduanchixuqudechuangxintupo。kexuejiezhengzhiliyujiangerzhedeyoushixiangjiehe,tongguotansuozhongxikangshuaicelvederongheyuzhuanhuayingyong,yixunzhaogengquanmian、有效的健康衰老方案。


2025年4月,國際頂級期刊《Cell》發表重磅綜述,在原有12個衰老生物學標誌物基礎上,新增細胞外基質變化和心理社會隔離兩大標誌,將衰老標誌物擴展至14個[1]。從(cong)現(xian)代(dai)醫(yi)學(xue)角(jiao)度(du)看(kan),十(shi)四(si)大(da)衰(shuai)老(lao)標(biao)誌(zhi)物(wu)涵(han)蓋(gai)了(le)從(cong)細(xi)胞(bao)分(fen)子(zi)層(ceng)麵(mian)到(dao)心(xin)理(li)社(she)會(hui)層(ceng)麵(mian)的(de)諸(zhu)多(duo)因(yin)素(su),每(mei)一(yi)個(ge)標(biao)誌(zhi)物(wu)都(dou)如(ru)同(tong)精(jing)密(mi)儀(yi)器(qi)中(zhong)的(de)齒(chi)輪(lun),相(xiang)互(hu)關(guan)聯(lian)、相互影響。


圖片來源:《Cell》綜述文章


在這一多標誌、係統性的衰老視角下,現代醫學幹預通常遵循從細胞、組織、器官到人體係統的邏輯推進。1665年,科學家首次發現“細胞”這個生命基本單位[2],它也是衰老起作用的最小生命單位。人體由40萬億個細胞組成,其衰老機製與目前科學界公認的十四大衰老標誌物[3]緊密相關。


當細胞開始老化,組織和器官功能也會隨之衰退。這就像身體裏的“鬧鍾”逐漸失靈,晚上輾轉難眠,白天昏昏沉沉,情緒容易煩躁,整個人陷入疲勞與精力不足的惡性循環。



而中醫在抗衰老領域也有著獨到的智慧和實踐。其中,中醫經典《黃帝內經》較為係統地記載了有關衰老和抗衰老的理論,並將其與“精、氣、血”的概念緊密相連。中醫認為,“精、氣、血”是維持生命活動的基本物質。



jingqixuedezhuangtaizhijiejuedinglexibaoweihuanjingdeyoulie,shixibaojiankangdegenbenbaozhang。jingqixuechongzu,xueguantongchang,yingyangheyangqinengshunlitongguoxueyesongdameiyigexibao,daixiefeiwuyenengjishipaichu,xibaoweihuanjingqingxinwending,xibaodeyigaoxiaojinxingnengliangdaixie、合成與修複,維持最佳功能[8]



然而,在衰老狀態下,精氣血虧虛情況出現時,管道運輸受阻,就會對細胞產生不良影響[9]。精不足則化氣無源,氣不足則溫煦、涼潤失司,推動、氣化、防禦等功能減退,諸髒腑功能低下、四肢百骸失於濡養[10][11]。這一過程遵循從外到內的規律,首先影響細胞微環境,進而影響細胞功能,最終導致細胞結構損傷[12][13]



據了解,為了找到抗衰更優解,長期致力於草本延衰領域研究的無限極(中國)有限公司嚐試融合中醫“精氣血”理論與現代細胞理論,探索中西融合整體抗衰新思路。


2024年底,無限極與劍橋大學、華南理工大學聯合申報的“十四五”國家重點研發計劃政府間國際科技創新合作專項-中國和歐洲國家聯合實驗室項目《中英健康與衰老聯合實驗室》成cheng功gong獲huo批pi,平ping台tai聚ju焦jiao草cao本ben延yan衰shuai領ling域yu,打da造zao差cha異yi化hua的de延yan衰shuai產chan品pin。過guo去qu十shi餘yu年nian裏li,從cong中zhong醫yi理li論lun創chuang新xin到dao基ji礎chu研yan究jiu,無wu限xian極ji在zai草cao本ben延yan衰shuai領ling域yu取qu得de了le豐feng碩shuo成cheng果guo,累lei計ji發fa表biao高gao水shui平ping論lun文wen40餘篇。



2020年nian,劍jian橋qiao無wu限xian極ji研yan究jiu中zhong心xin發fa現xian了le溶rong酶mei體ti對dui內nei質zhi網wang結jie構gou實shi時shi動dong態tai調tiao控kong的de動dong力li學xue機ji製zhi,並bing解jie析xi了le細xi胞bao器qi相xiang互hu運yun動dong的de因yin果guo性xing機ji製zhi,為wei篩shai選xuan天tian然ran來lai源yuan的de、具有抗衰作用的新原料/成分,以及研究產品發揮作用的機製,提供了全新的研究方向、分析方法和靶點。相關研究成果以論文《The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes》形式發表在世界權威學術期刊《Science》旗下的重要刊物《Science Advances》[14]


論文發表於《Science Advances》


2023年,劍橋無限極研究中心再次取得突破性成果,並在全球頂級科學期刊、生化研究方法領域排名第一的權威刊物《Nature Methods》上發表研究成果:基於AI的活細胞內質網結構動態分析的創新技術平台。可應用於中草藥健康產品的功能因子篩選、功效驗證和機製可視化研究,讓中草藥組方的功效說得清道得明[15]


論文發表於《Nature Methods》


除了以上研究,基於“精氣血”理論與十四大衰老標誌,無限極發現了可通過多靶點幹預衰老的中式細胞延衰核心組方。核心組方可以調控7個關鍵靶點,從“細胞環境修複、細胞充能、細胞新生”三個維度改善多重衰老表征,為抗衰提供了新的科學路徑。



衰老是一個由表及裏、循序漸進的多層次複雜過程。真正的年輕態應該是由內而外的綻放,當內在精氣血充盈,外在肌膚自然煥發光彩。期待未來有更多企業、高校、科研院所等力量加入,共同推進中西融合抗衰研究,提供更堅實的科學基礎和可行的實踐方案。


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[5]Putra C, Konow N, Gage M, York CG, Mangano KM. Protein Source and Muscle Health in Older Adults: A Literature Review. Nutrients. 2021 Feb 26;13(3):743. doi: 10.3390/nu13030743. PMID: 33652669; PMCID: PMC7996767.

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